Welcome to Ishikawa/Sato Laboratory! We study the interaction of laser pulses and ion beams with matter through theory and simulations. Our major research interest is ab-initio simulations (first-principles simulations, first-principle simulations) of atoms and molecules in femtosecond and attosecond laser pulses. When irradiated by intense laser pulses, electrons in atoms and molecules exhibit highly nonlinear responses. We reveal these dynamics, otherwise invisible, using computer simulations based on quantum mechanics. Our goal is to realize ultimate technology to observe and manipulate electron dynamics in the attosecond time scale. Electronic motion is a key factor to microscopically understand radiation effect on biomolecules. On the other hand, we also strive to develop methods to evaluate macroscopic dose distribution for heavy ion cancer therapy. Combining both micro- and macroscopic approaches, we hope to contribute to advanced radiation cancer therapy. We believe that sound scientific foundation makes technology including nuclear engineering reliable and resilient. We always welcome students and researchers passionate about interdisciplinary research across theory-experiment boundaries.